Caffeine is a stimulant drug used for mental alertness and to accelerate energy and power. It is also used to delay muscle fatigue as it goes deep into the muscle tissues.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Synthetic Guggulsterones, which is a form of orally administered guggulipid, which increases T3 (tryiidothyronine) levels in animal models. T3 is the conversion product of T4, which is produced by the thyroid gland. Thyroid hormone levels are closely involved in metabolic function. Increased thyroid levels can cause more fat to be burned and stored. While on a diet, the body responds by decreasing T3 levels, therefor decreasing metabolic rate. It is not known how guggulipid increases T3 levels. Guggul, also called guggulipid, is an ethyl acetate extract of the gum resin of the guggul tree.

Yohimbe, which when ingested, the body converts to yohimbine and assimilates it into the bloodstream. Yohimbe comes from the bark of a tree that grows primarily in Africa. Yohimbine, an alkaloid, is the primary active ingredient of yohimbe. Yohimbe is commonly used as an aphrodisiac and antioxidant. Yohimbe is also used as a vasodilator, which means that it increases blood flow to the extremities and appendages, this is one of the main reasons why it is found in many sexual aids.